Publications

  • Hur, Y.; Huynh, J.; Leong, E.; Dosanjh, R.; Charvat, A. F.; Vu, M. H.; Alam, Z.; Lee, Y. T.; Cabreros, C. C.; Carroll, E. C.; Hura, G. L.; Wang, N. The Differing Effects of a Dual Acting Regulator on SIRT1. Frontiers in Molecular Biosciences 2023, 10.
  • Huynh, A. T.*, Nguyen, T. N.*, Villegas, C. A.*, Montemorso, S., Strauss, B., Pearson, R. A., Graham, J. G., Oribello, J., Suresh, R., Lustig, B., Wang, N. Prediction and Confirmation of a Switch-like Region within the N-terminal Domain of hSIRT1. Biochem. Biophys. Rep. 2022, 30, 101275. (Authors with * contributed equally)
  • Weeks, A. M.; Wang, N.; Pelton, J. G.; Chang, M. C. Y. Entropy drives selective fluorine recognition in the fluoroacetyl-CoA thioesterase from Streptomyces cattleya. Proc. Natl. Acad. Sci. 115, E2193-E2201 (2018).
  • Wang, N., Lodge, J. M., Fierke, C. A. & Mapp, A. K. Dissecting allosteric effects of activator-coactivator complexes using a covalent small molecule ligand. Proc. Natl. Acad. Sci. 111, 12061–6 (2014).
  • Wang, N.,Majmudar, C. Y., Pomerantz, W.C., Gagnon, J. K., Sadowsky, J. D., Meagher, J. L., Johnson, T. J., Stuckey, J. A., Brooks, C. L. III, Wells, J. A., & Mapp, A. K. Ordering a dynamic protein via a small-molecule stabilizer. J. Am. Chem. Soc. 135, 3363–6 (2013).
  • Pomerantz, W.C., Wang, N., Lipinski, A. K., Wang, R., Cierpicki, T., & Mapp, A. K. Profiling the dynamic interfaces of fluorinated transcription complexes for ligand discovery and characterization. ACS Chem. Biol. 7, 1345–50 (2012).
  • Wands, A. M., Wang, N., Lum, J. K., Hsieh, J., Fierke, C. A. & Mapp, A. K. Transient-state kinetic analysis of transcriptional activator-DNA complexes interacting with a key coactivator. J. Biol. Chem. 286, 16238–16245 (2011).